![]() In addition to those curated from the literature, we added about 300 experimentally mapped promoters coming from our own high-throughput mapping efforts. We have now computational predictions for sigma(54) and five different promoter types of the sigma(70) family, as well as their corresponding -10 and -35 boxes. Transcription factors are classified by origin of their effectors and by gene ontology class. ![]() All the objects are supported by their corresponding evidences, now classified as strong or weak. Curation of original literature is, from now on, up to date for every new release. This paper summarizes the improvements, new biology and new features available in version 6.0. RegulonDB () is the primary reference database offering curated knowledge of the transcriptional regulatory network of Escherichia coli K12, currently the best-known electronically encoded database of the genetic regulatory network of any free-living organism. ![]()
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